Comparison of Fluid Resuscitation Regimens in Septic Heart Failure Patients Alexas Polk, Roger Reeder, Hunter Ingoe Southeastern Regional Medical Center - Lumberton, NC
Background/Purpose: The Surviving Sepsis Campaign recommends that all patients receive adequate fluid resuscitation for sepsis-induced hypotension within three hours of presentation, utilizing at least 30 mL/kg of intravenous crystalloid fluid. However, the guidelines make no recommendations for specific patient populations in which large volume fluid boluses may be detrimental. The purpose of this study is to assess current fluid resuscitation practices of septic heart failure patients in the emergency department at Southeastern Regional Medical Center.
Methodology: This retrospective, observational study evaluated adult patients admitted to Southeastern Regional Medical Center through the emergency department with diagnoses of sepsis and heart failure. The primary objective of the study is to evaluate the current fluid resuscitation practices of septic heart failure patients in the emergency department. The secondary objective of the study is to evaluate the effect of these practices on fluid and sepsis related outcomes. Patients were categorized and evaluated based on whether or not they were adequately fluid resuscitated, defined as receiving at least 30 mL/kg of intravenous crystalloid fluids in the emergency department.
Results: A total of 123 patients were evaluated in this study. Neither fluid resuscitation strategy had a statistically significant impact on secondary outcomes including diuretic usage, need for intubation, trend of lactate levels, need for vasopressors, ICU length of stay and mortality or hospital length of stay and mortality.
Conclusions: Various fluid resuscitation regimens in septic heart failure patients had no impact on fluid and sepsis related outcomes in patients admitted through the emergency department at Southeastern Regional Medical Center.
Presentation Objective: To assess the impact of various fluid resuscitation practices on the outcomes of septic heart failure patients.
Self-Assessment: What currently guides fluid resuscitation efforts in septic patients?
